mRNA Pipeline
Research
Browse:
Our mRNA pipeline shows the progress we’re making on clinical programs currently in development to create mRNA medicines for a wide range of diseases and conditions.
as-of May 01, 2026
Please click here for more information on our approved products
All Categories
Program Indication
ID #
Phase 1
Phase 2
Phase 3
Commercial
Respiratory Vaccines
Adults
COVID-19 vaccine
SPIKEVAX®
Commercial
COVID-19 vaccine
mNEXSPIKE®
Commercial
RSV vaccine
mRESVIA®
Commercial
Flu + COVID vaccine
mCOMBRIAX
Commercial
Flu vaccine
mRNA-1010
Phase 3
Pandemic Flu vaccine(in collaboration with CEPI)
mRNA-1018
Phase 3
RSV + hMPV vaccine
mRNA-1365
Phase 1
Adolescents and Pediatrics
RSV vaccinepediatrics
mRNA-1345
Phase 2
Latent & Other Vaccines
Enteric Viruses
Norovirus vaccine
mRNA-1403
Phase 3
Norovirus vaccine
mRNA-1405
Phase 2
Latent Viruses
CMV vaccinefor transplant recipients
mRNA-1647
Phase 2
EBV vaccineto prevent infectious mononucleosis
mRNA-1189
Phase 2
EBV vaccineto address long-term EBV sequelae
mRNA-1195
Phase 2
HIV vaccinein collaboration with IAVI
mRNA-1645
Phase 1
Bacterial
Lyme disease vaccine
mRNA-1975
Phase 2
Lyme disease vaccine
mRNA-1982
Phase 2
Public Health
Nipah vaccine
mRNA-1215
Phase 1
Mpox vaccine
mRNA-1769
Phase 2
Oncology Therapeutics
Intismeran Autogene (partnered with Merck)
Adjuvant melanoma
mRNA-4157
Phase 3
Adjuvant NSCLC
mRNA-4157
Phase 3
Adjuvant NSCLC non-pCR post-neoadjuvant treatment
mRNA-4157
Phase 3
Adjuvant Stage 1 NSCLC
mRNA-4157
Phase 3
Adjuvant Renal cell carcinoma (RCC)
mRNA-4157
Phase 2
Adjuvant Bladder cancer (MIBC)
mRNA-4157
Phase 2
Bladder cancer (NMIBC)
mRNA-4157
Phase 2
Metastatic melanoma
mRNA-4157
Phase 2
First-line metastatic squamous NSCLC
mRNA-4157
Phase 2
Early and advanced solid tumors
mRNA-4157
Phase 1
Cancer antigen therapies
Advanced solid tumors
mRNA-4359
Phase 2
Solid tumors
mRNA-4106
Phase 1
T-cell engagers
Multiple myeloma
mRNA-2808
Phase 1
Cell therapy enhancers
Solid tumors(in collaboration with Immatics)
mRNA-4203 + anzu-cel (IMA203)
Phase 1
Rare Disease Therapeutics
Rare Disease Intercellular Therapeutics
Propionic acidemia (PA)
mRNA-3927
Phase 2
Methylmalonic acidemia (MMA)
mRNA-3705
Phase 2
Cystic fibrosis (CF)(in collaboration with Vertex)
mRNA-3692
Phase 2
Abbreviations: CEPI, Coalition for Epidemic Preparedness Innovations; NSCLC, non-small cell lung cancer; MIBC, muscle-invasive bladder cancer; NMIBC, non-muscle invasive bladder cancer
as-of May 01, 2026
Please click here for more information on our approved products